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Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

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[Auditory brain-stem response in obstructive sleep apnea syndrome].

¹PUMC Hospital, Beijing.

Zhonghua Er Bi Yan Hou Ke Za Zhi

|January 1, 1991

Summary

Obstructive sleep apnea syndrome (OSAS) may affect auditory pathways. Auditory brain-stem responses (ABRs) showed abnormalities, and surgery did not significantly improve these auditory function measures.

Area of Science:

Neuroscience
Otolaryngology
Sleep Medicine

Background:

Obstructive sleep apnea syndrome (OSAS) is a prevalent condition with potential systemic effects.
Auditory pathway integrity can be impacted by various physiological changes.

Purpose of the Study:

To investigate the effects of OSAS on auditory brain-stem responses (ABRs).
To assess the impact of uvulopalatopharyngoplasty (UPPP) on ABR parameters in OSAS patients.

Main Methods:

Auditory brain-stem responses (ABRs) were recorded in 20 patients with OSAS.
ABRs were re-evaluated in 16 patients 1-2 months post-uvulopalatopharyngoplasty (UPPP).
Analysis focused on latencies (I, III, V) and intervals (I-III, I-V, III-V).

Main Results:

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Significant prolongation of average I, V latencies and III-V intervals observed in OSAS patients.
Statistically significant shortening of I-III intervals noted.
No significant changes in ABR parameters (except thresholds) were found post-UPPP.

Conclusions:

OSAS may exert detrimental effects on cochlear and auditory brain-stem structures.
Recovery of auditory brain-stem function following UPPP appears limited.
Further research is needed to understand the long-term auditory consequences of OSAS.