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How to Build a Laser Speckle Contrast Imaging (LSCI) System to Monitor Blood Flow
Published on: November 11, 2010
Statistics of local speckle contrast
Donald D Duncan1, Sean J Kirkpatrick, Ruikang K Wang
1Department of Biomedical Engineering, Oregon Health and Science University, 3303 SW Bond Avenue, Portland, Oregon 97239, USA. donald.duncan@bme.ogi.edu
Summary
Local laser speckle contrast, often assumed to be unity, varies significantly in localized regions. This study models this local contrast distribution using a log-normal function, linking its parameters to speckle size and neighborhood extent.
Area of Science:
- Optics and Photonics
- Image Processing
- Biomedical Imaging
Background:
- Laser speckle contrast is typically assumed to be unity in first-order analysis.
- Localized spatial region calculations in processing schemes often yield contrast values deviating from unity.
Purpose of the Study:
- To characterize the distribution of local laser speckle contrast.
- To model the local contrast using a log-normal distribution.
- To establish relationships between model parameters and physical properties like speckle size.
Main Methods:
- Analysis of local contrast calculated over localized spatial regions.
- Modeling the local contrast distribution using a log-normal probability distribution function.
- Expressing model parameters in terms of minimum speckle size and local neighborhood extent.
- Validation using Optical Coherence Tomography (OCT) data.
Main Results:
- Local laser speckle contrast exhibits a distribution of values that can differ from unity.
- A log-normal distribution accurately characterizes the local contrast.
- The parameters of the log-normal model are dependent on the minimum speckle size and the size of the local neighborhood used for calculation.
Conclusions:
- The local contrast of laser speckle is not always unity and follows a predictable distribution.
- The log-normal model provides a robust framework for understanding local speckle contrast variations.
- This model offers insights into data acquisition parameters and their impact on speckle analysis, particularly in OCT.

