Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

The Blood-brain Barrier

The Blood-brain Barrier

Cerebrospinal Fluid

Cerebrospinal Fluid

Cerebrospinal fluid (CSF) is a colorless liquid that flows around the brain and the spinal cord, playing a vital role in the protection, support, and overall function of the central nervous system (CNS). CSF production, circulation, and absorption are tightly regulated processes essential for the brain and spinal cord to function properly.
CSF Production
CSF is produced mainly in the choroid plexus, a network of capillaries and ependymal cells located within the ventricular system of the brain.

Organization of the Brain

Organization of the Brain

The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...

Functional Brain Systems: Limbic System

Functional Brain Systems: Limbic System

The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep brain...

Cranial and Spinal Meninges

Cranial and Spinal Meninges

The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...

The Vestibular System

The Vestibular System

The vestibular system is a set of inner ear structures that provide a sense of balance and spatial orientation. This system is comprised of structures within the labyrinth of the inner ear, including the cochlea and two otolith organs—the utricle and saccule. The labyrinth also contains three semicircular canals—superior, posterior, and horizontal—that are oriented on different planes.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Selective removal of visual working memory items at test.

Cerebral cortex (New York, N.Y. : 1991)·2026

Same author

Selective removal of visual working memory items at test.

bioRxiv : the preprint server for biology·2026

Same author

Contralateral delay activity as a marker of visual working memory capacity: A multi-site registered replication.

Cortex; a journal devoted to the study of the nervous system and behavior·2026

Same author

A unique neural signature of long-term memory encoding from EEG inter-electrode correlation.

Imaging neuroscience (Cambridge, Mass.)·2026

Same author

Past and present goals are represented concurrently during visual search.

PLoS biology·2026

Same author

Image memorability facilitates visual working memory formation: Evidence from contralateral delay activity.

Cognition·2026

Search research articles

Related Experiment Video

Updated: Jul 8, 2026

Isolating Immune Cells from Mouse Brain and Skull

Isolating Immune Cells from Mouse Brain and Skull

Published on: July 26, 2024

The bouncer in the brain.

Edward Awh¹, Edward K Vogel

¹Department of Psychology, University of Oregon, Eugene, OR 97403-1227, USA. awh@uoregon.edu

Nature Neuroscience

|December 28, 2007

Summary

This summary is machine-generated.

Individual differences in working memory may stem from how efficiently the brain filters information. A study found the basal ganglia act as this filter, with lower activity linked to less irrelevant information storage.

More Related Videos

Evaluation of Blood-Brain Barrier Breakdown in a Mouse Model of Mild Traumatic Brain Injury

Evaluation of Blood-Brain Barrier Breakdown in a Mouse Model of Mild Traumatic Brain Injury

Published on: October 18, 2024

A Repetitive Concussive Head Injury Model in Mice

A Repetitive Concussive Head Injury Model in Mice

Published on: October 12, 2016

Related Experiment Videos

Last Updated: Jul 8, 2026

Isolating Immune Cells from Mouse Brain and Skull

Isolating Immune Cells from Mouse Brain and Skull

Published on: July 26, 2024

Evaluation of Blood-Brain Barrier Breakdown in a Mouse Model of Mild Traumatic Brain Injury

Evaluation of Blood-Brain Barrier Breakdown in a Mouse Model of Mild Traumatic Brain Injury

Published on: October 18, 2024

A Repetitive Concussive Head Injury Model in Mice

A Repetitive Concussive Head Injury Model in Mice

Published on: October 12, 2016

Area of Science:

Cognitive Neuroscience
Neuroimaging
Human Brain Function

Background:

Individual differences in working memory capacity are significant.
Information filtering efficiency is a proposed mechanism underlying these differences.
The neural basis of this filtering process remains incompletely understood.

Purpose of the Study:

To investigate the role of specific brain regions in filtering relevant from irrelevant information.
To explore the neural correlates of individual differences in working memory efficiency.

Main Methods:

Functional magnetic resonance imaging (fMRI) was employed to measure brain activity.
Participants underwent tasks assessing working memory and information filtering.
Brain activity was analyzed in relation to task performance and stimulus relevance.

Main Results:

Activity in the basal ganglia prior to stimulus presentation was inversely correlated with the storage of irrelevant information.
This suggests the basal ganglia play a crucial role in suppressing or filtering out distractors.
The findings provide a neural basis for understanding working memory efficiency variations.

Conclusions:

The basal ganglia function as a critical filter for relevant information during working memory tasks.
Basal ganglia activity patterns can predict the degree of irrelevant information retained in working memory.
This research offers insights into the neural mechanisms underpinning cognitive control and memory limitations.