Related Experiment Videos
Morganella morganii sepsis with massive hemolysis
Jong Hoon Kim1, Chong Rae Cho, Tae Hyun Um
1Department of Internal Medicine, Inje University Ilsan Paik Hospital, Goyang, Korea.
Journal of Korean Medical Science
|December 29, 2007
Summary
Morganella morganii sepsis can cause fatal massive hemolysis, a previously unreported complication. This severe condition led to rapid death in an immunocompromised patient despite aggressive treatment.
Area of Science:
- Microbiology
- Infectious Diseases
- Hematology
Background:
- Morganella morganii is a facultative gram-negative rod.
- While some bacterial infections are linked to hemolysis, massive hemolysis from M. morganii sepsis is not previously documented.
- M. morganii infections can be severe in neonates and immunocompromised individuals.
Observation:
- A 59-year-old male patient with chemotherapy-induced neutropenia presented with sepsis.
- The patient exhibited massive hemolysis and metabolic acidosis.
- Despite prompt and aggressive medical intervention, the patient died within 6 hours of hospital admission.
Findings:
- Blood cultures confirmed the presence of Morganella morganii sepsis.
- This case demonstrates a fatal instance of massive hemolysis directly caused by M. morganii sepsis.
- The rapid progression of hemolysis and acidosis contributed to the patient's demise.
Implications:
- This report highlights a critical, previously unrecognized complication of M. morganii sepsis.
- Clinicians should consider M. morganii as a potential cause of massive hemolysis, particularly in neutropenic or immunocompromised patients.
- Early recognition and management of M. morganii sepsis may be crucial to prevent fatal outcomes.
Related Concept Videos
01:26Rocky Mountain Spotted Fever
Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
01:22Bacterial Meningitis I: Introduction
Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
01:27Disorders of Erythrocytes
Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...