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Updated: Jul 8, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
[Study of the chronic apical periodontitis influence upon the patient's organism status]
Abstract:
During clinical-immunological study of the patients with chronic apical periodontitis (CAP) some differences were found between the following categories--CAP involving not more than 2 teeth and plural CAP. There were found the changes of both general immunity indices and its local components. Chronic inflammation course in periodontal tissues led to imbalance between cellular and humoral local immune reactions. It was shown that the presence of protracted multiple infectious focuses in periodontal tissues led to organism sensitizing and secondary immune deficiency.
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