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A novel allele, HLA-G*010114, with a non-coding DNA base change in exon 2

A Arnaiz-Villena1, J I Serrano-Vela, R Reguera

  • 1Department of Immunology, Universidad Complutense, The Madrid Regional Blood Center, Madrid, Spain. aarnaiz@med.ucm.es

Tissue Antigens
|January 16, 2008
PubMed
Summary

The human leucocyte antigen (HLA)-G locus exhibits high DNA diversity but low protein variation, suggesting evolutionary pressure for functional invariance. This may be linked to its proposed immunotolerogenic role.

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