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Isolation and Cannulation of Cerebral Parenchymal Arterioles
Published on: May 23, 2016
Dissections of brain-supplying arteries
1Division of Cerebrovascular Disease, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA. lcaplan@bidmc.harvard.edu
Nature Clinical Practice. Neurology
|January 18, 2008
Summary
Cervical artery dissections, often caused by arterial wall tears, are increasingly diagnosed. Treatment typically involves antithrombotic medications, with a low recurrence rate for stroke or dissection.
Area of Science:
- Neurology
- Vascular Surgery
- Radiology
Background:
- Arterial dissections in the head and neck are increasingly recognized due to improved diagnostics and clinical awareness.
- These dissections stem from arterial wall stretching and tearing, leading to intramural hematoma.
- Symptoms commonly include headache and pain, with specific types causing ischemia, aneurysms, or hemorrhage.
Purpose of the Study:
- To review the current understanding of cervical artery dissections.
- To highlight diagnostic modalities and treatment approaches.
Main Methods:
- Review of clinical features and diagnostic imaging techniques for arterial dissections.
- Discussion of current treatment strategies and recurrence rates.
Main Results:
- Conventional angiography is optimal for visualization, though CT/MR angiography, MRI, and ultrasound are also effective.
- Subintimal dissections primarily cause brain and eye ischemia.
- Subadventitial dissections can lead to aneurysms, pseudoaneurysms, and subarachnoid hemorrhage.
Conclusions:
- Antithrombotic medications are the mainstay of treatment, despite a lack of randomized trial data.
- The recurrence rate of infarction or dissection following initial events is notably low.
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