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Updated: Jul 8, 2026
07:56
Evaluating Regional Pulmonary Deposition using Patient-Specific 3D Printed Lung Models
Published on: November 11, 2020
Age-dependent changes of airway obstruction parameters
S Nosal1, M Sutovska, G Nosalova
1Clinic of Children and Adolescents, Department of Pharmacology, Jessenius Faculty of Medicine, Comenius University, Martin, Slovakia. slavonosal@yahoo.com
Summary
This study assessed respiratory inductive plethysmography indices in infants. Older children (7-24 months) showed a decreased phase angle (phi) and increased Tme/Te compared to younger infants, with no sex differences observed.
Area of Science:
- Pediatric Pulmonology
- Respiratory Physiology
- Infant Health Monitoring
Background:
- Noncalibrated respiratory inductive plethysmography is used to assess infant breathing patterns.
- Understanding physiological respiratory index ranges in infants is crucial for accurate health assessments.
- Age-related changes in respiratory mechanics can impact diagnostic interpretations.
Purpose of the Study:
- To determine the physiological range of phase angle (phi) and Tme/Te indices in healthy children up to 24 months old.
- To investigate the influence of age and sex on these respiratory parameters.
- To evaluate the stability and age-dependency of phi and Tme/Te indices.
Main Methods:
- 127 healthy children up to 24 months of age were studied.
- Noncalibrated respiratory inductive plethysmography was performed in the supine position.
- Measurements of phase angle (phi) and Tme/Te were analyzed for age and sex differences.
Main Results:
- A significant decrease in phase angle (phi) was observed in children aged 7-24 months compared to those aged 0-6 months (P<0.001).
- Tme/Te values were significantly higher in older children (7-24 months) than in younger infants (P<0.05).
- No significant sex differences were found for either phi or Tme/Te.
Conclusions:
- Respiratory inductive plethysmography indices, phi and Tme/Te, exhibit age-dependent changes in infants up to 24 months.
- The Tme/Te index may be a more stable and less age-dependent parameter than the phase angle (phi).
- Further research is needed to confirm the clinical utility and interpretation of these indices in infant respiratory monitoring.
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