Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Prolactin-releasing peptide.

Steven H Lin1

  • 1Department of Radiation Oncology and Molecular Radiation Sciences, Sydney Kimmel Comprehensive Cancer Center, The Johns Hopkins Hospital, Baltimore, MD 21231, USA. slin37@jhmi.edu

Results and Problems in Cell Differentiation
|January 22, 2008
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cuproptosis-immunity crosstalk informs strategy to overcome immunotherapy resistance.

Cell·2026
Same author

Cellular architecture and neighborhood-informed virtual spatial tumor profiling from histopathology.

Cell·2026
Same author

SARS-CoV-2 mRNA Vaccination Improved Survival in NSCLC Treated With Radiotherapy.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer·2026
Same author

Long-Term Outcomes After Proton Therapy Versus Intensity Modulated Photon Radiation Therapy With Concurrent Chemotherapy for Locally Advanced Non-Small Cell Lung Cancer: Post Hoc Analysis of a Prospective Randomized Trial.

International journal of radiation oncology, biology, physics·2026
Same author

Ionizing radiation expands a p90RSK-activated patrolling monocyte subset: modulation by colchicine.

Frontiers in cardiovascular medicine·2026
Same author

FLASH Radiotherapy Mitigates Radiation-Induced Lymphopenia and Prevents Immunosuppression via Chk1-STAT3 Axis Modulation in a Preclinical Thoracic Irradiation Model.

International journal of radiation oncology, biology, physics·2026
Same journal

Application of Bioactive Natural Compounds to Promote Cell Proliferation and Migration in the Wound Healing Process.

Results and problems in cell differentiation·2026
Same journal

Mechanobiology of Myelin Generation/Regeneration in Health and Disease.

Results and problems in cell differentiation·2026
Same journal

Epigenetic Regulation of RUNX2 in Bone Mechanobiology.

Results and problems in cell differentiation·2026
Same journal

Integrating Mechanical Loading, Mechanotransduction, and Biological Responses in Musculoskeletal Tissues Across the Lifespan: Regulation Influenced by Cells, Extracellular Matrix, and Sex.

Results and problems in cell differentiation·2026
Same journal

Ciliary-Mediated Mechanotransduction in Skeletal Development and Diseases.

Results and problems in cell differentiation·2026
Same journal

Modulation of the Mechanosensory Matrisome by Serotonergic Signaling.

Results and problems in cell differentiation·2026
See all related articles

Prolactin-releasing peptide (PrRP) stimulates arachidonic acid release and has expanded functions beyond prolactin release. This review covers the PrRP system, its organismal roles, and therapeutic potential.

Area of Science:

  • Neuroendocrinology
  • G protein-coupled receptor research

Background:

  • Prolactin-releasing peptide (PrRP) was identified in the bovine hypothalamus.
  • It activates the orphan G protein-coupled receptor hGR3 (also known as GPR10).
  • Initial research focused on its role as a prolactin-releasing factor.

Purpose of the Study:

  • To review the current knowledge of the PrRP system.
  • To discuss the putative functions of PrRP in organisms.
  • To explore potential therapeutic implications of the PrRP system.

Main Methods:

  • Literature review of over 120 published papers on PrRP since 1998.
  • Analysis of the PrRP system's components and signaling pathways.
  • Synthesis of findings regarding PrRP's physiological roles.

Related Experiment Videos

Main Results:

  • The functional understanding of PrRP has significantly broadened beyond prolactin release.
  • The PrRP system is implicated in various physiological processes.
  • Extensive research has been conducted on PrRP since its discovery.

Conclusions:

  • The PrRP system plays a more diverse role in the organism than initially thought.
  • Further research into PrRP's functions may reveal novel therapeutic targets.
  • Understanding the PrRP system is crucial for advancing neuroendocrinology and related fields.