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Updated: Jul 8, 2026

Osmotic Drug Delivery to Ischemic Hindlimbs and Perfusion of Vasculature with Microfil for Micro-Computed Tomography Imaging
Published on: June 29, 2013
Current status of antivascular therapy and targeted treatment in the clinic
Olav Dahl1, Erling Dahl Borkamo, Oystein Fluge
1Institute of Medicine, University of Bergen Section of Oncology, Bergen, Norway. olav.dahl@helse-bergen.no
Abstract:
Antivascular and targeted therapy are now an integrated part of the treatment of myelogenous leukemias, GIST tumours, B-cell lymphomas and breast cancer. In various malignancies improved responses and prolongation of survival for several months is regularly reported. The progress in this field is relevant for hyperthermia. Heat has among other effects documented antivascular effects, and can be considered as one of the established methods in the field based on several randomised phase III studies. Hyperthermia should be considered for combination with other antiangiogenic agents.
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