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Published on: August 19, 2021
Low-grade endometrial stromal sarcoma with florid intravenous component
Keith Wing-Kit Lo1, Mei-Yung Yu, Tak-Hong Cheung
1Department of Obstetrics and Gynecology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, SAR, China. wklo@cuhk.edu.hk
Gynecologic and Obstetric Investigation
|January 25, 2008
Summary
Low-grade endometrial stromal sarcoma (LGESS) can significantly involve pelvic veins, mimicking intravenous leiomyomatosis. Early detection and surgical management of venous involvement in LGESS are crucial for patient outcomes.
Area of Science:
- Gynecologic Oncology
- Vascular Pathology
- Surgical Pathology
Background:
- Low-grade endometrial stromal sarcoma (LGESS) is a rare uterine malignancy.
- Vascular invasion is a known prognostic factor in uterine cancers.
- The specific pattern of extensive pelvic vein involvement in LGESS is infrequently reported.
Observation:
- A case of LGESS presented with extensive involvement of pelvic veins.
- The vascular infiltration pattern closely resembled intravenous leiomyomatosis.
- This presentation highlights a potential diagnostic challenge and underscores the importance of considering venous involvement.
Findings:
- Venous system involvement should be a key consideration in the clinical management of LGESS.
- Systematic screening for venous tumor invasion is essential at the time of metastasis or recurrence diagnosis.
- Surgical intervention is a feasible option for managing extensive venous recurrence of LGESS.
Implications:
- This case emphasizes the need for vigilance regarding vascular invasion in LGESS.
- Improved diagnostic strategies for detecting venous involvement in LGESS are warranted.
- Surgical expertise can facilitate the management of advanced or recurrent LGESS with venous extension.