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Sister Mary Joseph nodule: a case report
Andrea Baratta1, Risa J Gorin, Richard Costa
1Family Practice Residency, University of Medicine & Dentistry of New Jersey, School of Osteopathic Medicine, Stratford, USA. abcalleo@hotmail.com
Cutis
|February 6, 2008
Summary
Sister Mary Joseph nodule (SMJN) is a rare umbilical metastasis, often indicating visceral malignancy. Early diagnosis and histologic confirmation are crucial for prognosis, as SMJN typically signals advanced gastrointestinal or gynecologic cancer.
Area of Science:
- Oncology
- Gastroenterology
- Dermatology
Background:
- Sister Mary Joseph nodule (SMJN) is a rare clinical sign of metastatic cancer to the umbilicus.
- It often signifies an advanced gastrointestinal or gynecologic malignancy.
- SMJN is associated with a poor prognosis, with average survival around 10 months.
Observation:
- A 66-year-old male presented with an enlarging umbilical lesion.
- Histopathology confirmed adenocarcinoma.
- A comprehensive metastatic workup identified the sigmoid colon as the primary tumor site.
Findings:
- The case highlights a rare presentation of sigmoid colon adenocarcinoma manifesting as an umbilical metastasis.
- This underscores the importance of investigating umbilical lesions for underlying visceral malignancies.
- Accurate histopathological diagnosis is essential for appropriate patient management.
Implications:
- Umbilical metastases (SMJN) warrant a thorough investigation for occult primary tumors.
- Prompt diagnosis and staging are critical for determining treatment strategies and patient outcomes.
- This case emphasizes the diagnostic value of umbilical lesions in identifying advanced cancers.
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