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Detergents are used to purify the integral proteins of the membrane. The hydrophobic portion of the detergent can replace membrane phospholipids while solubilizing the membrane proteins. When detergent monomers reach a specific concentration in a solution called critical micelle concentration (CMC), they form micelles. Above CMC, the concentration of the detergent monomers remains in equilibrium with the micelle. The number of detergent monomers present in the CMC varies for each detergent, and...

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Related Experiment Video

Updated: Jul 7, 2026

Contrast-Matching Detergent in Small-Angle Neutron Scattering Experiments for Membrane Protein Structural Analysis and Ab Initio Modeling

Contrast-Matching Detergent in Small-Angle Neutron Scattering Experiments for Membrane Protein Structural Analysis and Ab Initio Modeling

Published on: October 21, 2018

Commonly used detergents.

¹National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.

Current Protocols in Molecular Biology

|February 12, 2008

Summary

This summary is machine-generated.

This appendix provides essential scientific data, covering common abbreviations, measurements, and chemical properties. It also details safe handling of hazardous materials and useful conversion factors for laboratory work.

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Area of Science:

Biochemistry
Laboratory Science
Chemical Safety

Background:

Scientific research relies on accurate data and standardized information.
Researchers often need quick access to fundamental constants, properties, and safety guidelines.
A centralized reference can improve efficiency and reduce errors in experimental design and execution.

Purpose of the Study:

To compile essential reference information for scientists.
To provide a convenient resource for common laboratory data and safety protocols.
To facilitate accurate calculations and safe practices in research settings.

Main Methods:

Compilation of commonly used abbreviations.
Inclusion of standard measurements and data for biological molecules.
Summarization of safety information for radioisotopes and hazardous chemicals.
Provision of conversion factors for laboratory equipment and units.

Main Results:

A comprehensive list of common scientific abbreviations.
Detailed characteristics of amino acids and nucleic acids.
Guidelines for the safe use of radioisotopes and hazardous chemicals.
Conversion tables for centrifuges, rotors, and other common factors.

Conclusions:

This appendix serves as a valuable quick-reference guide for researchers.
The provided information enhances laboratory efficiency and promotes safety.
Accessibility to basic scientific data is crucial for reproducible research.