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Contrast-Matching Detergent in Small-Angle Neutron Scattering Experiments for Membrane Protein Structural Analysis and Ab Initio Modeling

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¹National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.

Current Protocols in Immunology

|April 25, 2008

Summary

This summary is machine-generated.

This appendix provides a list of Epstein-Barr virus (EBV)-transformed B lymphoblastoid cell lines (B-LCL) and their Human Leukocyte Antigen (HLA) types. These cell lines are valuable resources for immunological and genetic research.

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Area of Science:

Immunology
Genetics
Cell Biology

Background:

Epstein-Barr virus (EBV)-transformed B lymphoblastoid cell lines (B-LCL) are widely used in immunological research.
Characterizing the Human Leukocyte Antigen (HLA) types of these cell lines is crucial for their application.
A standardized reference list of B-LCL and their HLA types is needed.

Purpose of the Study:

To compile a comprehensive list of reference Epstein-Barr virus (EBV)-transformed B lymphoblastoid cell lines (B-LCL).
To document the specific Human Leukocyte Antigen (HLA) types expressed by each listed B-LCL.
To provide a valuable resource for researchers in cellular immunity and histocompatibility studies.

Main Methods:

Compilation of existing data on EBV-transformed B-LCL.
Inclusion of documented Human Leukocyte Antigen (HLA) typing for each cell line.
Organization of the information into a clear, accessible appendix format.

Main Results:

A curated list of reference B-LCL is presented.
The specific HLA types (e.g., HLA-A, HLA-B, HLA-DR) for each cell line are detailed.
This resource facilitates the selection of appropriate cell lines for various research applications.

Conclusions:

The provided appendix serves as a critical reference for EBV-transformed B-LCL and their HLA types.
These characterized cell lines are essential for reproducible studies in cellular immunity.
The resource supports biochemical characterization of histocompatibility molecules and DNA-based typing controls.