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[RS3PE associated with tuberculosis].

F J Nicolás-Sánchez1, J R Rozadilla Sacanell, A M Gort Oromí

  • 1Servicio de Medicina Interna, Hospital de Santa María, Lleida. fnicolas@comll.cat

Anales De Medicina Interna (Madrid, Spain : 1984)
|February 15, 2008
PubMed
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Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) typically presents without infection. This case highlights a rare association between RS3PE and tuberculosis in an elderly patient.

Area of Science:

  • Rheumatology
  • Infectious Diseases
  • Geriatrics

Background:

  • Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) is a distinct clinical syndrome.
  • RS3PE typically affects the elderly, presenting with symmetrical polyarthritis and pitting edema, and is characterized by a negative rheumatoid factor.

Observation:

  • An 89-year-old patient presented with anorexia and edema of the hands and feet.
  • The patient had a negative rheumatoid factor, consistent with RS3PE.
  • A pulmonary infiltrate was noted on examination.

Findings:

  • Microbiological studies confirmed Mycobacterium tuberculosis infection.
  • This represents a previously undescribed association between RS3PE and tuberculosis.

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Implications:

  • This case expands the differential diagnosis for RS3PE.
  • Clinicians should consider infectious etiologies, particularly tuberculosis, in elderly patients presenting with RS3PE.
  • Early diagnosis and treatment of tuberculosis are crucial in patients with RS3PE.