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Updated: Jul 7, 2026
05:23
Gastric Mucosa Quantitative Polymerase Chain Reaction Analysis for Detecting Helicobacter pylori and Antibiotic Resistance
Published on: March 7, 2025
[Association between chronic urticaria and Helicobacter pylori]
Carlos L Pliego Reyes1, Nayeli Jiménez Saab, Javier Gómez Vera
1Hospital Regional Lic. Adolfo López Mateos del ISSSTE. dr_pliego_reyes@yahoo.com.mx
Revista Alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)
|February 27, 2008
Summary
Chronic urticaria patients show a significantly higher prevalence of Helicobacter pylori infection compared to healthy individuals. This study suggests a routine screening for H. pylori in chronic urticaria cases.
Area of Science:
- Gastroenterology
- Dermatology
- Infectious Diseases
Background:
- Chronic urticaria is a complex skin condition with unknown mechanisms.
- Potential causes include mechanical, autoimmune, and idiopathic factors.
- Helicobacter pylori infection is a proposed contributing factor.
Purpose of the Study:
- To investigate the association between chronic urticaria and Helicobacter pylori infection.
- Utilize endoscopic and histopathological methods to confirm the link.
Main Methods:
- A case-control study involving 72 patients (36 chronic urticaria, 36 controls).
- Clinical history, IgE levels, and gastric biopsies for H. pylori detection (Warthin Starry stain).
- Statistical analysis using SPSS (version 11) for correlation.
Main Results:
- Helicobacter pylori infection was found in 52.8% of chronic urticaria patients versus 11.1% in controls.
- A statistically significant association was observed (chi2 = 12.52, p < 0.002).
Conclusions:
- A clear association exists between chronic urticaria and Helicobacter pylori.
- Routine screening for H. pylori is recommended for patients diagnosed with chronic urticaria.
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