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Periungual hyperpigmentation in newborns.

Matilde Iorizzo1, Arnold P Oranje, Antonella Tosti

  • 1Department of Dermatology, University of Bologna, Bologna, Italy. matildeiorizzo@hotmail.com

Pediatric Dermatology
|February 29, 2008
PubMed
Summary
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Transient hyperpigmentation of the distal phalanx is observed in some fair-skinned newborns. This benign condition may persist longer than previously reported, fading after two years of age.

Area of Science:

  • Neonatology
  • Dermatology
  • Pediatrics

Background:

  • Hyperpigmentation of the distal phalanx is common in newborns with darker skin.
  • Recently, this finding has also been noted in fair-skinned newborns as a transient, benign condition.

Purpose of the Study:

  • To investigate the occurrence and characteristics of distal phalanx hyperpigmentation in fair-skinned newborns.
  • To compare findings in term and premature newborns.

Main Methods:

  • Observation of term and premature newborns.
  • Clinical assessment of hyperpigmentation in the distal phalanx of hands and feet.
  • Tracking resolution of hyperpigmentation over time.

Main Results:

  • No hyperpigmentation was observed in premature newborns.

Related Experiment Videos

  • Seven out of 40 (17.5%) fair-skinned, at-term newborns exhibited distal phalanx hyperpigmentation.
  • The hyperpigmentation resolved after 2 years of age, a longer duration than previously documented.

    • Conclusions:

    • Distal phalanx hyperpigmentation can occur in fair-skinned, at-term newborns as a benign, transient disorder.
    • The persistence of this condition may exceed previously reported timelines.
    • The etiology remains unknown, though maternal hormonal influence is a speculative factor.