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Optimal treatment of hypertension with diastolic heart failure

Dinko Susic1, Edward D Frohlich

  • 1Ochsner Clinic Foundation, New Orleans, LA 70121, USA.

Heart Failure Clinics
|March 4, 2008
PubMed

Insights

Diastolic heart failure (DHF) affects half of heart failure patients. Managing hypertension and using diuretics are key treatments for DHF, improving patient outcomes.

Area of Science:

  • Cardiology
  • Internal Medicine

Background:

  • Heart failure affects 5 million Americans.
  • Diastolic heart failure (DHF), or heart failure with preserved ejection fraction, accounts for at least half of all clinically overt heart failure cases.
  • DHF is defined by specific cardiac remodeling and functional abnormalities.

Purpose of the Study:

  • To summarize the characteristics and management of diastolic heart failure.
  • To highlight the importance of hypertension control and therapeutic agents in DHF management.

Main Methods:

  • Review of epidemiologic studies on heart failure prevalence.
  • Analysis of DHF characteristics including ventricular remodeling and stiffness.
  • Evaluation of therapeutic strategies for DHF.

Main Results:

  • Diastolic heart failure is prevalent, characterized by normal left ventricular end-diastolic volume, impaired relaxation, and increased stiffness.
  • Diuretics are crucial for managing DHF symptoms.
  • Hypertension treatment is fundamental for preventing and treating DHF.

Conclusions:

  • Effective management of DHF involves diuretics and rigorous blood pressure control.
  • Antihypertensive medications like ACE inhibitors, ARBs, calcium antagonists, and nitrates can reduce wave reflection.
  • Lifestyle modifications may also support DHF treatment.

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