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Related Concept Videos

Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving01:29

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving

Mechanistic models play a crucial role in algorithms for numerical problem-solving, particularly in nonlinear mixed effects modeling (NMEM). These models aim to minimize specific objective functions by evaluating various parameter estimates, leading to the development of systematic algorithms. In some cases, linearization techniques approximate the model using linear equations.
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
Mechanistic Models: Compartment Models in Individual and Population Analysis01:23

Mechanistic Models: Compartment Models in Individual and Population Analysis

Mechanistic models are utilized in individual analysis using single-source data, but imperfections arise due to data collection errors, preventing perfect prediction of observed data. The mathematical equation involves known values (Xi), observed concentrations (Ci), measurement errors (εi), model parameters (ϕj), and the related function (ƒi) for i number of values. Different least-squares metrics quantify differences between predicted and observed values. The ordinary least squares (OLS)...

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Related Experiment Video

Updated: Jul 7, 2026

Murine Model of Allergen Induced Asthma
08:05

Murine Model of Allergen Induced Asthma

Published on: May 14, 2012

Models of asthma: density-equalizing mapping and output benchmarking.

Julia-Annik Börger1, Niko Neye1, Cristian Scutaru1

  • 1Institute of Occupational Medicine, Charité-Universitätsmedizin Berlin, Free University Berlin and Humboldt-University Berlin, Ostpreussendamm 111, D-12207 Berlin, Germany.

Journal of Occupational Medicine and Toxicology (London, England)
|March 5, 2008
PubMed
Summary
This summary is machine-generated.

This study analyzed 3,489 publications on animal models of asthma from 1968-2006. Research is concentrated in a few countries, with mice being the most common species used in asthma research.

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Quantitative Mapping of Specific Ventilation in the Human Lung using Proton Magnetic Resonance Imaging and Oxygen as a Contrast Agent
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Published on: June 5, 2019

Related Experiment Videos

Last Updated: Jul 7, 2026

Murine Model of Allergen Induced Asthma
08:05

Murine Model of Allergen Induced Asthma

Published on: May 14, 2012

Quantitative Mapping of Specific Ventilation in the Human Lung using Proton Magnetic Resonance Imaging and Oxygen as a Contrast Agent
08:26

Quantitative Mapping of Specific Ventilation in the Human Lung using Proton Magnetic Resonance Imaging and Oxygen as a Contrast Agent

Published on: June 5, 2019

Area of Science:

  • * Pulmonary Medicine
  • * Immunology
  • * Pharmacology

Background:

  • * Understanding the molecular basis of bronchial asthma is crucial for developing new therapies.
  • * Various animal models of asthma have been developed to facilitate this research.
  • * Bibliometric data on the utilization of these diverse animal models is lacking.

Purpose of the Study:

  • * To establish a comprehensive database of existing experimental approaches using animal models of asthma.
  • * To analyze publication trends, geographical distribution, and research quality indicators.
  • * To identify preferred animal species and subject categories in asthma research.

Main Methods:

  • * Bibliometric analysis utilizing density-equalizing algorithms.
  • * Data retrieval from a Thomson Institute for Scientific Information database (1900-2006).
  • * Analysis of publication counts, country participation, citation rates, journal distribution, subject categories, and animal species.

Main Results:

  • * A total of 3,489 publications on animal models of asthma were identified between 1968 and 2006.
  • * Research is concentrated in 52 countries, with the US, Japan, and UK being the most prolific.
  • * Switzerland and New Zealand showed high research quality based on citation per item; immunology was the leading subject category, and mice were the most frequently used species.

Conclusions:

  • * The application of animal models in asthma research is geographically concentrated.
  • * Significant variations exist in the choice of animal species, reflecting differing research focuses.
  • * Further bibliometric analysis can guide future research directions and collaborations in asthma modeling.