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Published on: December 14, 2019
Embolisation of metachronous pseudoaneurysms complicating chronic pancreatitis
W R Pillay1, S Lalloo, S R Thomson
1Department of General Surgery, Addington Hospital, University of Natal, Durban, South Africa.
Background:
Pseudoaneurysm bleeding is a well-described complication of chronic pancreatitis. Reports of embolisation therapy for metachronous pseudoaneurysms in this condition are rare. We present such a patient and describe his management.
Case Outline:
A 5 1-year-old man with chronic pancreatitis who presented with recurrent occult major gastrointestinal bleeding underwent angiography on two separate occasions, 2 years apart. Initial intervention revealed the origin of the coeliac axis to be occluded or absent, and a splenic artery (SA) aneurysm, feeding via the superior mesenteric artery, was embolised. Subsequent angiography after a major bleed showed a new pseudoaneurysm in the head of pancreas feeding from an aberrant hepatic artery, which was embolised. The second angiogram confirmed persistent occlusion of the SA aneurysm and 6 months follow-up showed no evidence of recurrence of the second aneurysm.
Discussion:
The resolution of these metachronous pseudoaneurysms by angiographic embolisation attests to the validity of this approach as potentially definitive and repeatable therapy.
Insights
This study highlights successful embolisation therapy for rare, sequential pseudoaneurysms in chronic pancreatitis. Angiographic embolisation proved effective and repeatable for managing these complex gastrointestinal bleeding complications.
Area of Science:
- Interventional Radiology
- Gastroenterology
- Vascular Surgery
Background:
- Pseudoaneurysm bleeding is a known complication of chronic pancreatitis.
- Metachronous pseudoaneurysms (occurring at different times) are rarely reported in this context.
- Effective management strategies for recurrent pseudoaneurysm bleeding in chronic pancreatitis require further investigation.
Purpose of the Study:
- To present a case of metachronous pseudoaneurysm bleeding in chronic pancreatitis.
- To describe the successful management of these sequential pseudoaneurysms using angiographic embolisation.
- To evaluate the efficacy and repeatability of embolisation as a therapeutic option.
Main Methods:
- A 51-year-old male patient with chronic pancreatitis and recurrent gastrointestinal bleeding was treated.
- Two separate angiographic embolisation procedures were performed 2 years apart.
- Initial embolisation targeted a splenic artery aneurysm; the second targeted a pseudoaneurysm in the pancreatic head.
Main Results:
- The initial splenic artery aneurysm was successfully embolised.
- A subsequent, new pseudoaneurysm in the pancreatic head, fed by an aberrant hepatic artery, was also effectively embolised.
- Follow-up confirmed persistent occlusion of the splenic artery aneurysm and no recurrence of the second pseudoaneurysm at 6 months.
Conclusions:
- Angiographic embolisation is a valid and potentially definitive therapy for metachronous pseudoaneurysms in chronic pancreatitis.
- The procedure is repeatable, offering a viable solution for recurrent bleeding.
- This case demonstrates the successful application of embolisation in managing complex vascular complications of chronic pancreatitis.
Related Concept Videos
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Chronic Pancreatitis I: Introduction
Chronic Pancreatitis II: Pathophysiology
Chronic Pancreatitis II: Collaborative Care
Assessment:
Acute Pancreatitis I: Introduction
Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include: