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Acellular dermis-assisted breast reconstruction.

S L Spear1, P M Parikh, E Reisin

  • 1Department of Plastic Surgery, Georgetown University, 1st Floor PHC Building, 3800 Reservoir Road NW, Washington, DC 20007, USA.

Aesthetic Plastic Surgery
|March 14, 2008
PubMed
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Acellular dermis provides inferolateral support for tissue expanders in breast reconstruction, leading to low complication rates and aesthetically pleasing results. This method aids in timely reconstruction after mastectomy.

Area of Science:

  • Plastic Surgery
  • Breast Reconstruction
  • Biomaterials

Background:

  • Previous partial submuscular tissue expander placement for breast reconstruction had limitations.
  • These limitations included poor control of the lower pocket pole, thin flap coverage, and muscle migration.
  • Acellular dermis was investigated for its potential to provide inferolateral support.

Purpose of the Study:

  • To examine the safety and efficacy of using an acellular dermal sling.
  • To assess its role in providing inferolateral support during immediate breast reconstruction and expansion.

Main Methods:

  • Prospective study of 58 breasts in 43 women undergoing immediate breast reconstruction with tissue expanders and acellular dermis.
  • Devices were exchanged for implants after adjuvant therapy and expansion.

Related Experiment Videos

  • Patients were tracked for oncologic data, complications, and aesthetic outcomes.

    • Main Results:

    • The mean reconstruction time was 8.6 months.
    • The complication rate was 12% after expander/acellular dermis placement and 2.2% after implant exchange.
    • Aesthetic outcomes were comparable to control subjects.

    Conclusions:

    • Acellular dermis is a valuable adjunct for immediate prosthetic breast reconstruction.
    • Acellular dermis-assisted reconstruction demonstrates a low complication rate.
    • This technique yields aesthetically pleasing results and facilitates timely reconstruction.