[Vagal nerve stimulation for refractory epilepsy in children]
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Published on: January 7, 2019
Eli Heyman1, Eli Lahat, Gad Lotan
1Pediatric Neurology Department, Assaf Harofeh Medical Center and Sackler Faculty of Medicine, Tel Aviv University. eheyman@post.tau.ac.il
Insights
Epileptic disease involves recurrent seizures and affects all ages. For medication-resistant cases, options include ketogenic diets, surgery, or vagal nerve stimulation.
Area of Science:
- Neurology
- Epileptology
Context:
- Epileptic disease is characterized by recurrent seizures, impacting all age groups.
- While many cases achieve satisfactory seizure control with medication, a subset exhibits drug resistance.
- Drug-resistant epilepsy necessitates exploring alternative therapeutic strategies.
Purpose:
- To outline current and emerging treatment modalities for epilepsy.
- To highlight interventions for patients with medication-resistant epilepsy.
Summary:
- Epilepsy is defined by recurrent seizures, excluding those caused by fever or acute brain injury.
- Standard pharmacological treatments are effective for most individuals.
- For refractory cases, therapeutic options include ketogenic diets, neurosurgical interventions, and vagal nerve stimulation.
Impact:
- Provides an overview of epilepsy management strategies.
- Informs clinicians and patients about advanced treatment options for refractory epilepsy.
- Highlights vagal nerve stimulation as a viable alternative for non-surgical candidates.
Abstract:
Epileptic disease is defined as recurrent seizures not as a result of fever or acute cerebral insult. It is very common in all age groups. In the majority of cases, satisfactory control is being achieved, leading to normal life. However, in some cases, the disease is resistant to a variety of medications. In these cases, an attempt to decrease the number of epileptic episodes is done by trying other methods such as a ketogenic diet or neurosurgical interventions. Recently, a new modality of treatment with vagal nerve stimulation was introduced, particularly for cases resistant to medications and are not candidates for neurosurgical intervention.
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