Multiple pilomatricoma in the context of previous seminoma: discussion on the possible relationship

Multiple pilomatricomas are rare. In the literature, they have been associated with many conditions, although the most common association is with myotonic dystrophy. We present a new association not previously described in the literature, observed in a 28-year-old male with three pilomatricomas, who had been diagnosed with seminoma 15 months before the current diagnosis of multiple pilomatricomas. Concerning the current association, as well as many of those described in the literature, we also discuss whether they might be more than mere coincidences, maybe explained by some molecular alterations.