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Post-liver transplant mycotic aneurysm of the hepatic artery

Vinci S Jones1, Murthy S Chennapragada, David J E Lord

  • 1Department of Pediatric Surgery, The Children's Hospital at Westmead, Westmead, Sydney 2145, NSW, Australia. vincijones@yahoo.co.in

Journal of Pediatric Surgery
|March 25, 2008
PubMed
Abstract

Insights

Mycotic aneurysms of the hepatic artery are rare after liver transplantation in children. Early diagnosis and multidisciplinary treatment are vital for successful outcomes in pediatric liver transplant recipients.

Area of Science:

  • Hepatology
  • Transplant Surgery
  • Pediatric Cardiology

Background:

  • Mycotic aneurysm of the hepatic artery is a rare complication post-liver transplantation.
  • It occurs in 0%–3% of patients with a significant mortality rate of approximately 30%.
  • This report focuses on pediatric cases of mycotic aneurysms following liver transplantation.

Purpose of the Study:

  • To report on the occurrence and management of pediatric mycotic aneurysms of the hepatic artery after liver transplantation.

Main Methods:

  • A retrospective chart review was conducted over a 21-year period.
  • Identified patients who developed mycotic aneurysms of the hepatic artery post-liver transplantation.
  • Analyzed treatment strategies and outcomes for these pediatric patients.

Main Results:

  • Two pediatric patients were identified with mycotic aneurysms of the hepatic artery after liver transplantation.
  • One patient died due to aneurysm rupture before diagnosis.
  • The second patient survived after treatment with radiological coil embolization, surgical excision, hepatic artery ligation, and antibiotics.

Conclusions:

  • Mycotic aneurysms of the hepatic artery in pediatric liver transplant recipients are rare but serious complications.
  • Prompt multidisciplinary treatment, including early diagnosis, is essential for optimizing patient outcomes.
  • Successful management may involve a combination of radiological and surgical interventions alongside antibiotic therapy.

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