Related Experiment Video
Updated: Jul 6, 2026

Neonatal Murine Cochlear Explant Technique as an In Vitro Screening Tool in Hearing Research
Published on: June 8, 2017
[Neonatal hearing screening. A comparison of automatic auditory brainstem audiometry and otoacoustic emissions]
Louise Pedersen1, Troels Reinholdt Møller, Randi Wetke
1Arhus Universitetshospital, Arhus Sygehus, Øre-, Naese- og Halskirugisk Afdeling. lupe@studmed.au.dk
Insights
Automatic Auditory Brainstem Response (AABR) is a superior newborn hearing screening method compared to Transient-Evoked Oto-Acoustic Emission (TEOAE). AABR identifies more cases of hearing loss, despite longer screening times.
Area of Science:
- Audiology
- Neonatal Screening
- Hearing Health
Background:
- Congenital hearing loss affects approximately 250 newborns annually in Denmark.
- Early detection and treatment within six months are crucial for speech, language, and social development.
Purpose of the Study:
- To compare the efficacy of two recommended newborn hearing screening methods in Denmark: Automatic Auditory Brainstem Response (AABR) and Transient-Evoked Oto-Acoustic Emission (TEOAE).
Main Methods:
- A total of 1627 infants were screened bilaterally using both AABR and TEOAE.
- Data collected included screening time and referral rates for each method.
Main Results:
- AABR resulted in a referral rate of 4% (67 infants), significantly lower than TEOAE's 11% (177 infants) (p = 2.43 x 10-16).
- Five infants were diagnosed with hearing loss after further examination.
- Average screening time for AABR was 6.6 minutes, compared to 3.8 minutes for TEOAE.
Conclusions:
- AABR is recommended as the primary screening method due to its higher detection rate.
- While AABR has higher equipment costs and time usage, it reduces the need for subsequent audiology examinations compared to TEOAE.
Introduction:
The annual birth rate in Denmark is 65,000. Approximately 100 of these children have a congenital bilateral hearing loss which requires treatment. Furthermore, it is expected that yet another 150 newborns have a unilateral hearing loss. Treatment of the hearing loss within the first six months is fundamental in order to ensure optimal use of speech and language, as well as normal social adaptation. The purpose of this study is to compare the two screening methods for hearing loss in newborns as recommended in Denmark--ie. Transient-Evoked Oto-Acoustic Emission (TEOAE) and Automatic Auditory Brainstem Response (AABR).
Materials And Methods:
During a period of six months, 1627 children were bilaterally screened with both AABR and TEOAE. The equipment used was Bio-logic's ABaer hearing screening system. Time usage and the number of refers was recorded.
Results:
Of the 1627 children, 67 (4% ) were referred on one or both ears when using AABR, compared to 177 (11% ) when using TEOAE, which is a statistically significant difference (p = 2.43 x 10-16). Re-screening and further examinations in the Department of Audiology identified five children as suffering from a hearing loss. The average time used to perform AABR was 6.6 min.s compared to 3.8 min.s for TEOAE.
Conclusion:
AABR is well chosen as primary screening method. The time usage and equipment costs related to AABR exceed those of TEOAE, but this seems acceptable considering the larger number of re-screenings and further examinations in the Department of Audiology when using TEOAE.
