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Updated: Jul 6, 2026

Quadruple Immunostaining of the Olfactory Bulb for Visualization of Olfactory Sensory Axon Molecular Identity Codes
06:32

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Published on: June 5, 2017

BIG-2 mediates olfactory axon convergence to target glomeruli

Tomomi Kaneko-Goto1, Sei-Ichi Yoshihara, Haruko Miyazaki

  • 1Laboratory for Neurobiology of Synapse, RIKEN Brain Science Institute, Saitama 351-0198, Japan.

Neuron
|March 28, 2008
PubMed
Summary

BIG-2/contactin-4 is an axonal glycoprotein crucial for forming the odor map. In BIG-2-deficient mice, olfactory sensory neurons innervate multiple glomeruli, disrupting the odor map organization.

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