Inhaled antimicrobial therapies for respiratory infections
Shin-Woo Kim1, Joseph L Kuti, David P Nicolau
1Center for Anti-Infective Research and Development, Hartford Hospital, 80 Seymour Street, Hartford, CT 06102, USA.
Abstract:
Inhaled antimicrobial therapy is attractive because of its potential to provide high concentrations of antimicrobials to the site of active respiratory infections while avoiding systemic toxicity. Many antimicrobials have been used in inhaled preparations, including aminoglycosides, colistin sodium, cephalosporins, penicillins, vancomycin, amphotericin B, and several antiviral compounds. This review highlights available data on inhaled antimicrobials, antifungals, and antivirals for the prevention and treatment of infections of the respiratory tract.
More Related Videos
Related Concept Videos
Inhaled Medications
Drugs Used in Lower Respiratory Disorders: Overview
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
Drugs Used in Upper Respiratory Disorders: Overview
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Microbiota of the Respiratory Tract
Acute Respiratory Failure-V
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by anesthetizing...


