Related Experiment Video
Updated: Jul 6, 2026

06:15
Using Enclosed Y-Mazes to Assess Chemosensory Behavior in Reptiles
Published on: April 7, 2021
Toxicologic information resources for reptile envenomations.
Jude McNally1, Keith Boesen, Leslie Boyer
1Arizona Poison and Drug Information Center, College of Pharmacy, University of Arizona, 1295 N. Martin, Room B308, Tucson, AZ 85721, USA. mcnally@pharmacy.arizona.edu
Summary
The United States imports millions of reptiles, including venomous snakes. Envenomations from these exotic species, often from amateur collectors, pose serious medical risks.
Area of Science:
- Veterinary Medicine
- Toxicology
- Herpetology
Background:
- The U.S. is the world's largest reptile importer, with 1.5-2.0 million households owning reptiles.
- Snakes constitute 11% of reptile imports, and up to 9% of these may be venomous.
- Envenomations by non-indigenous venomous species are rare but serious medical emergencies.
Purpose of the Study:
- To provide toxicologic information resources for managing snake envenomations.
- To highlight the risks associated with exotic venomous reptiles in the U.S.
Main Methods:
- Review of existing literature on exotic reptile imports and envenomations.
- Identification of primary sources of exotic envenomation incidents.
Main Results:
- Exotic venomous snake envenomations primarily occur in academic settings (universities, zoos, museums) and from amateur collectors.
- Amateur collectors involved in importation, propagation, and trade are a significant source of these incidents.
Conclusions:
- Effective management of exotic snake envenomations requires accessible toxicologic resources.
- Public health awareness and regulation may be needed to mitigate risks from the exotic pet trade.
More Related Videos
Related Concept Videos
Toxic Reactions: Overview
When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Toxidromes: Clinical Features
Toxidromes are specific patterns of symptoms resulting from toxic substance exposure. They help in the identification and treatment of poisoning. The symptoms of each toxidrome group indicate poisoning by a certain class of chemicals or drugs.1. Sympathomimetic: Stimulates the sympathetic nervous system. Symptoms include agitation, increased heart rate (HR), blood pressure (BP), respiratory rate (RR), temperature, and pupil size. Drugs like cocaine and amphetamines, along with tremors and...
Anticholinesterase Agents: Poisoning and Treatment
Anticholinesterases, also known as cholinesterase inhibitors, work by blocking the breakdown of acetylcholine, leading to its accumulation in the synaptic cleft. This accumulation indirectly enhances both muscarinic and nicotinic actions. These agents are classified as reversible or irreversible based on their mechanism of action.
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is slower than the...
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is slower than the...
Toxicity Testing in Animals
Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
Drug Toxicity: Overview
Drug toxicity quantifies the harm a compound causes to an organism, varying by dose and potentially impacting whole systems or specific organs like the liver. Toxic reactions may arise from venomous insect or spider bites, with effects ranging from mild symptoms to severe outcomes such as brain damage or death. Common forms of acute poisoning include ethanol intoxication and overdose of pain or fever medications, with substances like GHB and heroin being particularly lethal at doses close to...
Antidotes
Antidotes are medicinal substances used to counteract the harmful effects of toxins or drugs in the body. They function in various ways, each uniquely designed to combat specific toxic compounds.
Specific antidotes operate by inhibiting the enzymes that control biochemical pathways, reducing the production of harmful metabolites.
An example of an antidote is atropine, which counteracts the detrimental effects of cholinesterase inhibitors. It achieves this by deactivating muscarinic receptors,...
Specific antidotes operate by inhibiting the enzymes that control biochemical pathways, reducing the production of harmful metabolites.
An example of an antidote is atropine, which counteracts the detrimental effects of cholinesterase inhibitors. It achieves this by deactivating muscarinic receptors,...

