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[Localization of bcl-2 antiapoptotic protein in the human placenta]

D E Korzhevskiĭ, V A Otellin, A N Starorusskaia

    Morfologiia (Saint Petersburg, Russia)
    |April 17, 2008
    PubMed

    The aim of this investigation was to study the distribution of bcl-2 antiapoptotic protein in various structures of human placenta using immunocytochemical methods. Syncytiotrophoblast was found to have the greatest bcl-2 immunoreactivity, while cytotrophoblastic elements, connective tissue cells of the villi and the blood vessel walls were bcl-2-negative. It is suggested that accumulation of bcl-2 in the syncytiotrophoblast may reflect its high resistance to detrimental factors.

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