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Granulocyte-colony stimulating factor for the treatment of ritodrine-induced neutropenia

Masashi Kikkawa1, Shigeki Matsubara, Masaaki Takatoku

  • 1Department of Obstetrics, Gynecology, Jichi Medical University, Shimotsuke, Tochigi, Japan.

The Journal of Obstetrics and Gynaecology Research
|April 17, 2008
PubMed

We report on three pregnant women with ritodrine-induced neutropenia who were successfully treated with granulocyte-colony stimulating factor (G-CSF). The neutropenia occurred after continuous intravenous infusion of ritodrine for preterm labor. Ritodrine was discontinued and G-CSF was administered. Neutrophil counts returned to normal an average of 4.3 days after the administration. No infectious morbidity or adverse side-effects occurred in the mothers or infants. G-CSF is one possible treatment in women with ritodrine-induced neutropenia.

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