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Pyruvate kinase deficiency and malaria.

Kodjo Ayi1, Gundula Min-Oo, Lena Serghides

  • 1McLaughlin-Rotman Centre for Global Health, University Health Network-Toronto General Hospital, Toronto.

The New England Journal of Medicine
|April 19, 2008
PubMed
Summary

Pyruvate kinase deficiency protects against Plasmodium falciparum malaria infection. This erythrocyte enzyme disorder may offer a protective advantage against malaria in endemic regions.

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