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Related Experiment Video

Updated: Jul 5, 2026

Recording Synaptic Plasticity in Acute Hippocampal Slices Maintained in a Small-volume Recycling-, Perfusion-, and Submersion-type Chamber System
09:51

Recording Synaptic Plasticity in Acute Hippocampal Slices Maintained in a Small-volume Recycling-, Perfusion-, and Submersion-type Chamber System

Published on: January 1, 2018

Synaptic plasticity in the hippocampal slice preparation.

Z A Bortolotto1, W W Anderson, J T Isaac

  • 1MRC Centre for Synaptic Plasticity, Bristol, United Kingdom.

Current Protocols in Neuroscience
|April 23, 2008
PubMed
Summary
This summary is machine-generated.

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This study details optimal methods for investigating synaptic plasticity, the brain

Area of Science:

  • Neuroscience
  • Cellular and Molecular Neuroscience

Background:

  • Synaptic plasticity is crucial for learning and memory.
  • In vitro electrophysiology in brain slices is a common method to study it.

Purpose of the Study:

  • To outline special considerations for studying synaptic plasticity in hippocampal slices.
  • To provide principles applicable to other brain slice preparations.

Main Methods:

  • Standard in vitro electrophysiological techniques.
  • Application to hippocampal slice preparations.

Main Results:

  • Discussion of special considerations for optimal study.
  • Principles applicable across different brain slice models.

More Related Videos

Improved Preparation and Preservation of Hippocampal Mouse Slices for a Very Stable and Reproducible Recording of Long-term Potentiation
09:39

Improved Preparation and Preservation of Hippocampal Mouse Slices for a Very Stable and Reproducible Recording of Long-term Potentiation

Published on: June 26, 2013

Investigation of Synaptic Tagging/Capture and Cross-capture using Acute Hippocampal Slices from Rodents
11:29

Investigation of Synaptic Tagging/Capture and Cross-capture using Acute Hippocampal Slices from Rodents

Published on: September 4, 2015

Related Experiment Videos

Last Updated: Jul 5, 2026

Recording Synaptic Plasticity in Acute Hippocampal Slices Maintained in a Small-volume Recycling-, Perfusion-, and Submersion-type Chamber System
09:51

Recording Synaptic Plasticity in Acute Hippocampal Slices Maintained in a Small-volume Recycling-, Perfusion-, and Submersion-type Chamber System

Published on: January 1, 2018

Improved Preparation and Preservation of Hippocampal Mouse Slices for a Very Stable and Reproducible Recording of Long-term Potentiation
09:39

Improved Preparation and Preservation of Hippocampal Mouse Slices for a Very Stable and Reproducible Recording of Long-term Potentiation

Published on: June 26, 2013

Investigation of Synaptic Tagging/Capture and Cross-capture using Acute Hippocampal Slices from Rodents
11:29

Investigation of Synaptic Tagging/Capture and Cross-capture using Acute Hippocampal Slices from Rodents

Published on: September 4, 2015

Conclusions:

  • Optimized electrophysiological techniques enhance the study of synaptic plasticity.
  • Methodological considerations are key for reproducible results in neuroscience research.