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Quantified assessment of terminal density and innervation
David I Finkelstein1, Davor Stanic, Clare L Parish
1Howard Florey Institute, University of Melbourne, Parkville, Victoria, Australia.
Abstract:
Stereological methods allow for the determination of cell numbers, terminal densities, and, subsequently, the estimation of terminal arbor size within a given brain nucleus. This unit provides an explanation for determining the terminal arbor size of dopaminergic neurons of the nigrostriatal pathway in rodents. In contrast to previously used single-axon reconstructions, these stereological methods allow for quick and easy determination of terminal arbor size.
