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Gas-phase reactivity of aromatic sigma,sigma-biradicals toward dinucleoside phosphates
Linan Yang1, John J Nash, Michael J Yurkovich
1Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA.
Abstract:
In order to improve the understanding of the interactions of aromatic sigma,sigma-biradicals with DNA, the reactivity of three isomeric sigma,sigma-biradicals toward four dinucleoside phosphates was studied in a mass spectrometer. The dinucleoside phosphates were evaporated into the mass spectrometer by using laser-induced acoustic desorption (LIAD). The results demonstrate that the structure of the sigma,sigma-biradical and the base sequence of the dinucleoside phosphate can have a major influence on these reactions.
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