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Updated: Jul 5, 2026

Static Adhesion Assay for the Study of Integrin Activation in T Lymphocytes
Published on: June 13, 2014
Key molecules involved in receptor-mediated lymphocyte activation
J J O'Shea1, J A Johnston, J Kehrl
1National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, Maryland, USA.
Abstract:
This unit, along with Unit 11.9B, provides a summary of our current knowledge about various signaling pathways critical to the function of immune cells. Here, our understanding of T cell receptor (TCR)- and B cell receptor (BCR)-mediated signaling is summarized. A schematic representation of immunologically relevant cytokine receptors and the Janus Family Kinases (JAKs) that is activated through these receptors is provided, along with details about molecules involved in interleukin 2 mediated signal transduction.
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