Cytokine, growth factor, and chemokine ligand database
1Laboratory of Immunology, Baltimore, MD, USA.
Abstract:
Cytokines, chemokines, and growth factors are soluble proteins produced by leukocytes and other cell types, which act as chemical communicators between cells and tissues within the body. These proteins mediate a number of functions, ranging from effects on cell growth, differentiation, survival, and a number of effector activities. The main purpose of this unit is to provide an easy-to-use reference summarizing some of the current information on well-established cytokine, growth factore, and chemokine ligands. The information provided is confined largely to alternative names, protein properties, genetic chracteristics, chromosomal localization, cellular expression patters, cellular-tissue targets, stimuli regulating expression, functional properties, expression analysis, and clinical utility.
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