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Updated: Jul 5, 2026

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Published on: July 5, 2022
[Management of diabetes mellitus in young children]
Luis Eduardo P Calliari1, Osmar Monte
1Unidade de Endocrinologia Pediátrica, Departamento de Pediatria, Faculdade de Ciências Médicas, Santa Casa de São Paulo, SP, Brasil. caliari@uol.com.br
Insights
Type 1 diabetes in young children is rare but increasing globally. Early diagnosis and intensive, individualized family-centered care are crucial for managing this condition due to unique challenges in this age group.
Area of Science:
- Pediatrics
- Endocrinology
- Metabolic Disorders
Background:
- Type 1 diabetes mellitus (T1DM) in children under 5 years old is uncommon but shows a rising global incidence.
- Diagnosis is often delayed, with patients frequently presenting with advanced ketoacidosis.
- Young children's dependency necessitates early and comprehensive family involvement in T1DM management.
Purpose of the Study:
- To highlight the challenges and critical management strategies for type 1 diabetes in very young children.
- To emphasize the importance of early diagnosis and tailored treatment approaches.
Main Methods:
- This study reviews current literature and clinical guidelines on pediatric type 1 diabetes management.
- Focuses on the specific physiological and behavioral characteristics of children under 5 years old.
Main Results:
- Delayed diagnosis is common, leading to severe complications like ketoacidosis.
- Children under 5 exhibit atypical hypoglycemic symptoms, irregular eating and activity patterns, and heightened insulin sensitivity.
- Individualized insulin therapy and consistent glucose monitoring are paramount for effective glycemic control.
Conclusions:
- Intensive, family-centered care is essential for managing T1DM in children under 5.
- Individualized treatment plans and vigilant monitoring are key to preventing complications and achieving good metabolic outcomes.
Abstract:
The occurrence of type 1 diabetes mellitus in children under 5-years-old is rare, but its incidence has been growing all over the world. The diagnosis is usually delayed and the patient presents advanced states of ketoacidosis. After the diagnosis, it is extremely crucial the involvement of the family in the treatment from the beginning, due to the dependency of the young children. The attention focused on the patient must be intense, since there are no evident hypoglycemic symptoms, the food intake and physical activities are irregular and there is higher insulin sensitivity. Insulin administration has to be individualized, and glucose monitoring is essential to obtain a good control.
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