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[Prevalence of mite hypersensitivity in children with asthma]

Shi-yong Zhao1, Yi Wei, Xiao-bing Li

  • 1Pediatric Department, Jinhua General Hospital, Jinhua 321000, China. jhzsyhj@163.com

Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi = Chinese Journal of Parasitology & Parasitic Diseases
|April 30, 2008
PubMed

Insights

The most common asthma allergens in Jinhua children are Dermatophagoides pteronyssinus and Dermatophagoides farinae mites. Blomia tropicalis also triggers asthma and may cross-react with other common mite allergens.

Area of Science:

  • Allergen immunotherapy
  • Pediatric allergy
  • Immunology

Context:

  • Asthma is a prevalent chronic respiratory disease in children.
  • Mite allergens are significant triggers for allergic asthma.
  • Understanding local allergen prevalence is crucial for effective management.

Purpose:

  • To identify the primary mite allergens responsible for asthma in children in the Jinhua region.
  • To assess the prevalence rates of Dermatophagoides pteronyssinus, Dermatophagoides farinae, and Blomia tropicalis sensitization.
  • To investigate potential cross-reactivity between these mite allergens.

Summary:

  • A skin prick test study was conducted on asthma patients in Jinhua from October 2005 to September 2006.
  • Dermatophagoides pteronyssinus (80.6%) and Dermatophagoides farinae (77.8%) showed higher positive rates than Blomia tropicalis (61.1%).
  • Blomia tropicalis-sensitive cases exhibited high cross-reactivity to D. pteronyssinus (100%) and D. farinae (95.9%), suggesting shared allergenic components.

Impact:

  • Identifies D. pteronyssinus and D. farinae as key allergens in pediatric asthma in this region.
  • Suggests Blomia tropicalis plays a role and may exhibit cross-reactivity, influencing diagnostic and therapeutic strategies.
  • Provides data for targeted allergen avoidance and immunotherapy protocols for childhood asthma.

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