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Published on: February 6, 2019
Forward-planning intensity-modulated radiotherapy technique for prostate cancer
Mohamed Metwaly1, Awaad Mousa Awaad2, El-Sayed Mahmoud El-Sayed3
1Radiation Physics Department, Faculty of Science, Ain Shams University, Cairo.
Journal of Applied Clinical Medical Physics
|May 2, 2008
Summary
Modified dynamic arc therapy (M-DAT) in the prone position improves prostate cancer treatment by delivering precise radiation doses while better protecting the rectum. This technique offers enhanced rectal sparing compared to other methods.
Area of Science:
- Radiation Oncology
- Medical Physics
- Cancer Treatment
Background:
- Intensity-modulated radiotherapy (IMRT) is a standard for prostate cancer.
- Optimizing dose distribution and organ-at-risk sparing remains a challenge.
Purpose of the Study:
- To evaluate a modified dynamic arc therapy (M-DAT) technique for prostate and seminal vesicle irradiation.
- To compare M-DAT with simplified intensity-modulated arc therapy (SIMAT) and assess patient positioning for rectal dose reduction.
Main Methods:
- M-DAT utilized 350-degree arcs and conformal fields with dynamic/hard wedges.
- The technique was applied to 10 supine and 10 prone patients.
- Dosimetric comparison with SIMAT was performed, including rectal dose analysis.
Main Results:
- M-DAT in the prone position significantly reduced mean rectal dose (22.5 Gy) compared to supine M-DAT (30.2 Gy) and SIMAT (39.4 Gy).
- Rectal dose-volume parameters were consistently lower in prone M-DAT.
- Calculated and measured doses showed good agreement (max deviation 3.5%), with high accuracy in dose distribution.
Conclusions:
- Single-phase M-DAT with prone positioning provides excellent target coverage and superior rectal sparing.
- M-DAT has replaced conventional conformal radiotherapy and SIMAT for prostate cancer treatment in the department.
