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Related Experiment Videos

Osteoporosis in men.

Sundeep Khosla1, Shreyasee Amin, Eric Orwoll

  • 1Endocrine Research Unit, Guggenheim 7, College of Medicine, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA. khosla.sundeep@mayo.edu

Endocrine Reviews
|May 3, 2008
PubMed
Summary
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Osteoporosis in men is a growing public health concern, leading to significant fractures and mortality. Early diagnosis and treatment, including lifestyle changes and medication, are crucial for prevention in aging men.

Area of Science:

  • Gerontology
  • Endocrinology
  • Orthopedics

Background:

  • Osteoporosis and fractures in men are increasingly recognized as significant health issues, contributing to morbidity and mortality.
  • Male osteoporosis is diverse, encompassing age-related bone loss, idiopathic osteoporosis, and secondary causes.
  • Hormonal changes, particularly declining sex steroids, and reduced osteoblast function contribute to bone loss in aging men.

Purpose of the Study:

  • To highlight the public health significance of osteoporosis in aging men.
  • To discuss the heterogeneous nature and pathogenesis of osteoporosis in men.
  • To review diagnostic criteria and treatment strategies for male osteoporosis.

Main Methods:

  • Review of current literature on male osteoporosis.

Related Experiment Videos

  • Analysis of factors contributing to bone loss in men.
  • Evaluation of diagnostic approaches and therapeutic interventions.

    • Main Results:

    • Hip and vertebral fractures in men increase morbidity and mortality.
    • Diagnosis often uses male-specific bone mineral density reference ranges.
    • Treatment efficacy for men is comparable to that in women.

    Conclusions:

    • Increased awareness of male osteoporosis among healthcare providers and the public is essential.
    • Comprehensive management including lifestyle modifications and pharmacotherapy is key.
    • Effective prevention strategies are needed to mitigate fracture risk in the aging male population.