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[Osteoporosis and fractures associated with drugs]
Peter Vestergaard1, Lars Rejnmark, Leif Mosekilde
1Arhus Sygehus, Osteoporoseklinikken, Arhus C. p-vest@post4.tele.dk
Abstract:
Drugs can affect the skeleton in different ways. Antiepileptic drugs were not associated with any major fracture risk. Lithium was associated with a decreased fracture risk. Insulin, sulphonylureas and metformin were associated with a decreased risk, whereas glitazones were associated with an increased risk. Blood pressure lowering drugs, thiazide diuretics and nitroglycerin were associated with a decreased risk of fractures, whereas amiodarone and loop diuretics were associated with an increased risk. Pain medication varied from no effect to an increased fracture risk.
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