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Clofibrate and dalargin increase luminol-dependent chemiluminescence of mouse blood
1N. N. Semenov Institute of Chemical Physics, Russian Academy of Sciences, Moscow. kar_12225@orc.ru
Bulletin of Experimental Biology and Medicine
|May 7, 2008
Abstract:
The effects of hypolipidemic drug clofibrate and polypeptide dalargin on activity of the neutrophil peroxidase system in mice were studied using the method of luminol-enhanced chemiluminescence. Clofibrate and dalargin increased the chemiluminescence of mouse whole blood. Their combined use several-fold potentiated this effect. It is expected that combined use of hypolipidemics and polypeptides will open a new trend in the search for stimulators of oxygen-dependent nonspecific immunity.

