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Updated: Jul 5, 2026
09:34
Development of a More Sensitive and Specific Chromogenic Agar Medium for the Detection of Vibrio parahaemolyticus and Other Vibrio Species
Published on: November 8, 2016
Lower extremity infections by vibrio vulnificus
G Mouzopoulos1, M Stamatakos, M Tzurbakis
1Department of Evangelismos Hospital, Athens, Greece.
Chirurgia (Bucharest, Romania : 1990)
|May 7, 2008
Summary
Vibrio vulnificus infections can lead to severe limb necrosis and sepsis, often requiring amputation. Early suspicion and prompt treatment are crucial for managing this serious Gram-negative pathogen.
Area of Science:
- Microbiology
- Infectious Diseases
- Clinical Medicine
Background:
- Vibrio vulnificus is a Gram-negative pathogen found in marine environments.
- It causes local infections in healthy individuals and severe septicemia in those with liver disease.
Purpose of the Study:
- To present four complicated cases of Vibrio vulnificus infection.
- To highlight the severe outcomes and management challenges associated with these infections.
Main Methods:
- Retrospective review of clinical and laboratory records.
- Follow-up of four patients with complicated Vibrio vulnificus infections over a mean of 4.2 years.
Main Results:
- Three patients required urgent leg amputation due to extensive necrosis and septic complications.
- One patient developed calcaneus osteomyelitis three years after the initial injury, despite soft tissue excision.
Conclusions:
- High clinical suspicion is essential for diagnosing Vibrio necrotizing fasciitis, particularly in endemic areas.
- Prophylactic antibiotics for swimmers in endemic regions may be considered to prevent infection.
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