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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Treatment Resistent Cancers02:56

Treatment Resistent Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...

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Related Experiment Video

Updated: Jul 5, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
08:49

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

[Supportive care for malignant melanoma].

P Mohr1

  • 1Elbeklinikum Buxtehude, Am Krankenhaus 1, 21614, Buxtehude, Deutschland. Peter.Mohr@elbekliniken.de

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|May 9, 2008
PubMed
Summary
This summary is machine-generated.

Optimal supportive care is crucial for malignant melanoma patients undergoing systemic therapy, including chemotherapy and immunotherapy. Management of side effects like nausea, bone marrow failure, fatigue, and skin issues is detailed.

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Area of Science:

  • Oncology
  • Dermatology
  • Pharmacology

Context:

  • Systemic therapy for malignant melanoma involves chemotherapy, immunotherapy, and combination treatments.
  • Optimal supportive care is a critical component of managing patients undergoing these therapies.

Purpose:

  • To provide detailed recommendations for managing common and significant side effects associated with systemic therapy for malignant melanoma.
  • To address key supportive care aspects including nausea, vomiting, bone marrow failure, fatigue, and cutaneous side effects.

Summary:

  • Systemic treatments for malignant melanoma necessitate comprehensive supportive care strategies.
  • Key supportive care areas include antiemesis, hematologic support, fatigue mitigation, and dermatologic management.
  • The abstract outlines specific recommendations for addressing these dermato-oncologic challenges.

Impact:

  • Enhances patient quality of life during cancer treatment.
  • Aims to improve treatment adherence and outcomes by proactively managing side effects.
  • Provides a clinical guide for healthcare professionals managing melanoma patients.