[Metabolic syndrome: epidemiology and its risks].
D Lameira1, S Lejeune, J-J Mourad
1Unité de Médecine Interne et HTA, CHU Avicenne-APHP, 125 rue de Stalingrad, 93009 Bobigny cedex 09, France.
Annales De Dermatologie Et De Venereologie
|May 24, 2008
Summary
Metabolic syndrome prevalence is increasing globally, driven by obesity. French prevalence is lower than in North America and Europe, but metabolic syndrome significantly elevates risks for type 2 diabetes and cardiovascular disease.
Area of Science:
- Cardiology
- Endocrinology
- Public Health
Background:
- Rising global prevalence of metabolic syndrome linked to obesity and sedentary lifestyles.
- Metabolic syndrome is a cluster of conditions increasing risk for type 2 diabetes and cardiovascular disease.
- Previous studies indicate significant cardiovascular risks associated with metabolic syndrome.
Purpose of the Study:
- To analyze the prevalence of metabolic syndrome in France using different definitions.
- To assess the clinical value of identifying metabolic syndrome in various populations.
Main Methods:
- Utilized National Cholesterol Education Program (NCEP) and International Diabetes Federation (IDF) criteria for prevalence assessment.
- Evaluated the association between metabolic syndrome and cardiovascular disease (CVD) risk.
- Examined the diagnostic value of metabolic syndrome in general, hypertensive, and type 2 diabetes mellitus populations.
Main Results:
- Metabolic syndrome prevalence in France varied significantly by definition, lower than in North America and other European countries.
- Prevalence ranged from 11.7% (men) and 7.5% (women) by NCEP to 26% (men) and 18.4% (women) by IDF.
- Metabolic syndrome presence nearly doubles cardiovascular morbidity and mortality risk.
- Informative value demonstrated in general and hypertensive populations, but limited in type 2 diabetes mellitus patients.
Conclusions:
- Metabolic syndrome prevalence in France is lower compared to other Western regions, yet remains a significant public health concern.
- Identifying metabolic syndrome is crucial for cardiovascular risk stratification in the general and hypertensive populations.
- The clinical utility of metabolic syndrome identification is limited for cardiovascular risk assessment in individuals with type 2 diabetes mellitus.
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