Related Experiment Video
Updated: Jul 5, 2026

Visual and Microscopic Evaluation of Streptomyces Developmental Mutants
Published on: September 12, 2018
Effects of pH shock on the secretion system in Streptomyces coelicolor A3(2)
Yoon Jung Kim1, Jae Yang Song, Soon-Kwang Hong
1Department of Chemical and Biomolecular Engineering (The Brain Korea 21 Program), Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea.
Abstract:
Effects of pH shock on the secretion system of S. coelicolor A3(2) have been investigated at a transcriptional level by using DNA microarrays. Actinorhodin secretion was observed to be highly enhanced when an acidic-pH shock was applied to surface grown cultures of S. coelicolor A3(2). In this culture, a gene of actVA-orf1 encoding a putative efflux pump or transporter protein for actinorhodin was strongly upregulated. A major number of efflux pumps for other metabolites and a major number of secretion proteins for protein secretion were also observed to be upregulated with pH shock. The secretion of actinorhodin was observed to be remarkably enhanced in liquid culture as well.
More Related Videos
11:16A Hydroponic Co-cultivation System for Simultaneous and Systematic Analysis of Plant/Microbe Molecular Interactions and Signaling
Published on: July 22, 2017
09:34Identification of Growth Inhibition Phenotypes Induced by Expression of Bacterial Type III Effectors in Yeast
Published on: March 30, 2010
Related Concept Videos
Other Stress Responses in Bacteria
Stringent Response in E. coli
Factors Influencing Microbial Growth: pH
Streptococcal Pharyngitis