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Updated: Jul 5, 2026

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Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
Published on: September 21, 2017
Chimeric (alpha-amino acid + nucleoside-beta-amino acid)n peptide oligomers show sequence specific DNA/RNA
Khirud Gogoi1, Vaijayanti A Kumar
1Division of Organic Chemistry, National Chemical Laboratory, Pune, 411008, India. k.gogoi@ncl.res.in
Abstract:
An alpha/beta-peptide backbone oligonucleotide comprising natural alpha-amino acids alternating with a beta-amino acid component derived from thymidine sequence specifically recognizes and binds to deoxy- and ribo-oligoadenylates in triplex mode.
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