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Updated: Jul 5, 2026

Protein Digestion, Ultrafiltration, and Size Exclusion Chromatography to Optimize the Isolation of Exosomes from Human Blood Plasma and Serum
Published on: April 13, 2018
[Human serum albumin: isoforms and analbuminemia]
1Aarhus Universitet, Institut for Medicinsk Biokemi, Arhus C. ukh@biokemi.au.dk
Abstract:
Persons with human serum albumin and a genetic variant are relatively common, whereas variant homozygotes are rare. About 65 structurally different variants are known. There is no clear relationship between bisalbuminemia and disease, and therefore isoforms are detected either because of a very pronounced increase in ligand binding or because of a modified electrophoretic mobility. The latter albumins may have modified binding and/or immunological properties. Analbuminemia is a rare but relative benign, homozygote condition in which especially the lipid metabolism is affected.
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