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A Direct, Early Stage Guanidinylation Protocol for the Synthesis of Complex Aminoguanidine-containing Natural Products
Published on: September 9, 2016
Total synthesis of sanguiin H-5
Xianbin Su1, David S Surry, Richard J Spandl
1Department of Chemistry, University of Cambridge, Cambridge, UK.
Organic Letters
|May 29, 2008
Abstract:
Using an atropdiastereoselective oxidative biaryl coupling as the key step, the total synthesis of the ellagitannin natural product sanguiin H-5 is reported. Both organomagnesium and organozinc based metalation methodologies were used to efficiently construct the strained medium-ring core of the natural product.
