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Updated: Jul 4, 2026

Field Postmortem Rabies Rapid Immunochromatographic Diagnostic Test for Resource-Limited Settings with Further Molecular Applications

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Radiesse-induced herpes zoster.

Bryan Sires¹, Steven Laukaitis, Pegi Whitehouse

¹Allure Facial Laser and Medispa, Kirkland, Washington 98033, U.S.A. bryan@aeamail.com

Ophthalmic Plastic and Reconstructive Surgery

|June 4, 2008

Summary

Facial filler injections like Radiesse can trigger herpes simplex virus (HSV) reactivation, presenting as herpetic lesions. Prompt antiviral treatment is crucial for effective management of these rare complications.

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Area of Science:

Dermatology
Infectious Diseases

Background:

Radiesse, a calcium hydroxylapatite filler, is FDA-approved for correcting deep nasolabial folds.
Complications associated with Radiesse injections are infrequently reported.

Observation:

A patient developed herpes-like skin lesions post-Radiesse injection in the glabella.
Symptoms included vesicles, erythema, and pustules within the trigeminal nerve distribution.

Findings:

Initial antibiotic treatment was ineffective, but oral antivirals led to rapid improvement.
Herpetic symptoms resolved within a month following antiviral therapy.

Implications:

Physicians should consider herpes reactivation in patients presenting with facial lesions after filler injections.
Early initiation of antiviral therapy is recommended for suspected herpetic infections post-cosmetic procedures.